Obesity (external fat) is associated with internal obesity and fatty matter clogging up the arteries of the body (including the pudendal artery which supplies blood to the penis). Additionally, obesity can have a negative effect on our sex hormone balance (the balance of testosterone and estrogens), further contributing to sexual dysfunction. The fatty tissue present in obese abdomens contains abundant amounts of the enzyme aromatase—functioning to convert testosterone to estrogen—literally emasculating us! High blood pressure will cause the heart to have to work harder to get the blood flowing through the increased resistance of the arteries. Blood pressure lowering medications will treat this, but as a result of the decreased pressure, there will be less blood flow through the pudendal arteries. Thus blood pressure medications, although very helpful to prevent the negative affects of hypertension—heart attacks, strokes, etc.—will contribute to sexual dysfunction. High cholesterol will cause fatty plaque buildup in our arteries, compromising blood flow and contributing to sexual dysfunction. Tobacco constricts blood vessels and impairs blood flow through our arteries. Stress causes a surge of adrenaline release from the adrenal glands. The effect of adrenaline is to constrict blood vessels and decrease sexual function. Thus is the physiologic explanation for the all-too-common occurrence of performance anxiety. Interestingly, men with priapism (a prolonged and painful erection) are often treated with penile injections of an adrenaline-like chemical to bring down the erection.
Online Pharmacy India E.D. may be divided into organic (physical) causes and psychological causes. Clues to organic causes are the presence of a disease process or the use of a medication that is known to give rise to E.D., gradually deteriorating erections, or the loss of early morning and nocturnal erections. Clues to psychogenic causes are the presence of a psychological process (such as depression, stress, anxiety, breakup of a relationship, death of a loved one, etc.), sudden onset of erectile difficulty, intact early morning and nocturnal erections, and the ability to obtain an erection with masturbation although not with intercourse.